ATG14L (ATG14) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14.
Isotype	IgG
Formulation	ATG14 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	ATG14 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54 kDa
Gene Name	autophagy related 14
Database Link	NP_055739 Entrez Gene 305831 RatEntrez Gene 100504663 MouseEntrez Gene 22863 Human UniProt ID Q6ZNE5
Background	ATG14 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.
Synonyms	ATG14L; BARKOR; KIAA0831
Reference Data

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