GABARAP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	GABARAP antibody was raised against a 19 amino acid peptide near the amino terminus of human GABARAP.
Isotype	IgG
Formulation	GABARAP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	GABARAP Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	13 kDa
Gene Name	GABA type A receptor-associated protein
Database Link	NP_009209 Entrez Gene 56486 MouseEntrez Gene 58974 RatEntrez Gene 11337 Human UniProt ID O95166
Background	GABARAP Antibody: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.
Synonyms	ATG8A; GABARAP-a; MM46
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Regulation of autophagy

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