WDR5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL, IF: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	WDR5 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human WDR5.
Isotype	IgG
Formulation	WDR5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	WDR5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	WD repeat domain 5
Database Link	NP_060058 Entrez Gene 11091 Human UniProt ID P61964
Background	WDR5 Antibody: WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.
Synonyms	BIG-3; CFAP89; SWD3
Reference Data
Protein Families	Druggable Genome

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