GOLGA5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	GOLGA5 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GOLGA5.
Isotype	IgG
Formulation	GOLGA5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	GOLGA5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Predicted Protein Size	Predicted: 64, 80 kDa; Observed: 65, 78 kDa
Gene Name	golgin A5
Database Link	NP_005104 Entrez Gene 27277 MouseEntrez Gene 299258 RatEntrez Gene 9950 Human UniProt ID Q8TBA6
Background	GOLGA5 Antibody: GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1). It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2). As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4). Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5).
Synonyms	GOLIM5; ret-II; RFG5
Reference Data
Protein Families	Druggable Genome, Transmembrane

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