TCF12 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL, ICC: 10 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TCF12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCF12.
Isotype	IgG
Formulation	TCF12 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TCF12 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transcription factor 12
Database Link	AAH50556 Entrez Gene 6938 Human UniProt ID Q99081
Background	TCF12 Antibody: TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
Synonyms	bHLHb20; CRS3; HEB; HsT17266; HTF4
Reference Data

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