SIPA1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, IF: 20 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1.
Isotype	IgG
Formulation	SIPA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	SIPA1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	signal-induced proliferation-associated 1
Database Link	AAH10492 Entrez Gene 6494 Human UniProt ID Q96FS4
Background	SIPA1 Antibody: Signal-induced proliferation 1 (SIPA1) is a member of the SIPA1 family of RapGAPs, a family of mitogen-induced GTPase activating proteins. SIPA1 exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. When abnormally or prematurely expressed, SIPA1 may also hamper mitogen-induced cell cycle progression and may increase metastases in human cancers.
Synonyms	SPA1
Reference Data

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