BAPX1 (NKX3-2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	BAPX1 antibody was raised against a 19 amino acid synthetic peptide near the center of human BAPX1.
Isotype	IgG
Formulation	BAPX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	BAPX1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NK3 homeobox 2
Database Link	NP_001180 Entrez Gene 12020 MouseEntrez Gene 682329 RatEntrez Gene 579 Human UniProt ID P78367
Background	BAPX1 Antibody: BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.
Synonyms	BAPX1; NKX3.2; NKX3B; SMMD
Reference Data

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