PGP9.5 (UCHL1) Chicken Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1:2,500, IF: 1:500
Reactivity	Human, Rat
Host	Chicken
Clonality	Polyclonal
Immunogen	Recombinant full length human UCHL1 purified from E. coli
Isotype	IgY
Formulation	total IgY fraction in PBS + 10 mM NaN3.
Purification	Total IgY fraction
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	24 kDa
Gene Name	ubiquitin C-terminal hydrolase L1
Database Link	NP_004172 Entrez Gene 29545 RatEntrez Gene 7345 Human UniProt ID P09936
Background	The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Synonyms	HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Parkinson's disease

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