GAPDHS Mouse Monoclonal Antibody [Clone ID: 1D4]

Specifications

Product Data
Clone Name	1D4
Applications	IF, WB
Recommend Dilution	WB: 1:1,000, IF: 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified porcine GAPDH
Isotype	IgM
Formulation	total IgM fraction + 10 mM NaN3.
Purification	Total IgM fraction--concentrated culture supernatant
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38 kDa
Gene Name	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Database Link	NP_055179 Entrez Gene 14447 MouseEntrez Gene 66020 RatEntrez Gene 26330 Human UniProt ID O14556
Background	This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq]
Synonyms	GAPD2; GAPDH-2; GAPDS; HEL-S-278; HSD-35
Reference Data
Protein Families	Druggable Genome

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