FTO Mouse Monoclonal Antibody [Clone ID: 5-2H10]

Specifications

Product Data
Clone Name	5-2H10
Applications	WB
Recommend Dilution	WB: 1:1,000, IF: 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Isotype	IgG
Formulation	100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	58 kDa
Gene Name	fat mass and obesity associated
Database Link	NP_001073901 Entrez Gene 26383 MouseEntrez Gene 291905 RatEntrez Gene 79068 Human UniProt ID Q9C0B1
Background	This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq]
Synonyms	ALKBH9; BMIQ14; GDFD
Reference Data

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