COBRA1 (NELFB) Mouse Monoclonal Antibody [Clone ID: F7E4]

Specifications

Product Data
Clone Name	F7E4
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant full length human COBRA1 purified from E. coli
Isotype	IgG1
Formulation	100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	62 kDa
Gene Name	negative elongation factor complex member B
Database Link	NP_056271 Entrez Gene 58202 MouseEntrez Gene 311796 RatEntrez Gene 25920 Human UniProt ID Q8WX92
Background	NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]). [supplied by OMIM]
Synonyms	COBRA1; NELF-B
Reference Data
Protein Families	Transcription Factors

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