L3MBTL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 365 and 723 of L3MBTL
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	l(3)mbt-like 1 (Drosophila)
Database Link	NP_056293 Entrez Gene 241764 MouseEntrez Gene 26013 Human UniProt ID Q9Y468
Background	This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Synonyms	dJ138B7.3; H-L(3)MBT; L3MBTL; ZC2HC3
Note	Seq homology of immunogen across species: mouse (88%)
Reference Data
Protein Families	Transcription Factors

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