PSMC3 Rabbit Polyclonal Antibody

CAT#: TA308441

Rabbit polyclonal antibody to PSMC3 (proteasome (prosome, macropain) 26S subunit, ATPase, 3)



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CNY 6,281.00


货期*
5周

规格
    • 100 ul

Product images

经常一起买 (4)
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Recombinant protein of human proteasome (prosome, macropain) 26S subunit, ATPase, 3 (PSMC3), 20 µg
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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
Reactivity Human, Zebrafish, Chicken, Bovine, Rhesus Monkey, X. tropicalis, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 51 and 361 of PSMC3 (Uniprot ID#P17980)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 49 kDa
Gene Name proteasome 26S subunit, ATPase 3
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq]
Synonyms TBP1
Note Seq homology of immunogen across species: Mouse (100%), Zebrafish (100%), Xenopus Tropicalis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Proteasome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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