Phosphoserine phosphatase (PSPH) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Pig, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 175 of PSPH (Uniprot ID#P78330)
Isotype	IgG
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	phosphoserine phosphatase
Database Link	NP_004568 Entrez Gene 100678 MouseEntrez Gene 304429 RatEntrez Gene 5723 Human UniProt ID P78330
Background	The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq]
Synonyms	PSP; PSPHD
Note	Seq homology of immunogen across species: Mouse (93%), Pig (96%), Rat (94%), Bovine (94%)
Reference Data
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Glycine, serine and threonine metabolism, Metabolic pathways

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