NPEPPS Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Bovine, X. tropicalis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 328 and 648 of NPEPPS (Uniprot ID#P55786)
Formulation	1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	99 kDa
Gene Name	aminopeptidase puromycin sensitive
Database Link	NP_006301 Entrez Gene 19155 MouseEntrez Gene 50558 RatEntrez Gene 9520 Human UniProt ID P55786
Background	This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq]
Synonyms	AAP-S; MP100; PSA
Note	Seq homology of immunogen across species: Rat (97%), Bovine (96%), Xenopus tropicalis (85%)
Reference Data
Protein Families	Druggable Genome, Protease

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