EPS8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Xenopus, Rhesus Monkey, X. tropicalis, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 761 and 822 of EPS8 (Uniprot ID#Q12929)
Isotype	IgG
Formulation	1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	92 kDa
Gene Name	epidermal growth factor receptor pathway substrate 8
Database Link	NP_004438 Entrez Gene 13860 MouseEntrez Gene 2059 Human UniProt ID Q12929
Background	This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
Synonyms	DFNB102
Note	Seq homology of immunogen across species: Mouse (100%), Xenopus laevis (92%), Xenopus Tropicalis (92%), Rhesus Monkey (100%)
Reference Data
Protein Families	Druggable Genome

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