BAP29 (BCAP29) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	BAP29 antibody was raised against a 17 amino acid peptide from near the center of human Bap29 Bap29 antibody is specific for isoform a of Bap29 .
Isotype	IgG
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	B-cell receptor-associated protein 29
Database Link	NP_001008405 Entrez Gene 12033 MouseEntrez Gene 298943 RatEntrez Gene 55973 Human UniProt ID Q9UHQ4
Background	Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors (3). Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins (3). Bap29 possesses multiple isoforms.
Synonyms	BAP29
Reference Data
Protein Families	Druggable Genome, Transmembrane

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