UNC5C Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	IF: 50ug/ml.
Reactivity	Human, Mouse, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence NCTVSEEPTGID, from the internal region of the protein sequence according to NP_003719.2.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	unc-5 netrin receptor C
Database Link	NP_003719 Entrez Gene 22253 MouseEntrez Gene 478485 DogEntrez Gene 8633 Human UniProt ID O95185
Background	This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq]
Synonyms	UNC5H3
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Axon guidance

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