FOXC1 Goat Polyclonal Antibody
CAT#: TA302875
Goat Polyclonal Antibody against FOXC1
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CNY 5371.00
货期*
5周
规格
| Cited in 5 publications. |
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Specifications
| Product Data | |
| Applications | FC, WB |
| Recommend Dilution | ELISA: 1:32,000. WB: 0.5-1.5µg/ml. |
| Reactivity | Human, Mouse, Zebrafish |
| Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence RTSGAFVYDCSKF, from the C Terminus of the protein sequence according to NP_001444.1. |
| Isotype | IgG |
| Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | forkhead box C1 |
| Database Link | |
| Background | This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq] |
| Synonyms | ARA; FKHL7; FREAC-3; FREAC3; IGDA; IHG1; IRID1; RIEG3 |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
Citations (5)
| The use of this Antibodies has been cited in the following citations: |
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Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification
,Almubarak, A;Lavy, R;Srnic, N;Hu, Y;Maripuri, D;Kume, T;Berry, F;,
bioRxiv
[FOXC1]
|
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Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation
,null,
eLife
,PubMed ID 32510325
[FOXC1]
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|
FOXC1 Regulates Expression of Prostaglandin Receptors Leading to an Attenuated Response to Latanoprost
,Doucette, LP;Footz, T;Walter, MA;,
Invest. Ophthalmol. Vis. Sci.
,PubMed ID 29847662
[FOXC1]
|
|
Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation
,Fatima, A;Wang, Y;Uchida, Y;Norden, P;Liu, T;Culver, A;Dietz, WH;Culver, F;Millay, M;Mukouyama, YS;Kume, T;,
J. Clin. Invest.
,PubMed ID 27214551
[FOXC1]
|
|
Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients
,Ito, YA;Goping, IS;Berry, F;Walter, MA;,
Cell Death Dis
,PubMed ID 24556684
[FOXC1]
[Human; WB] |
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