SORBS1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ELISA: 1:16,000. WB:2.5µg/ml.
Reactivity	Human, Mouse, Rat, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-GTFPGNYVKPLYL, from the C Terminus of the protein sequence according to NP_006425.2; NP_056200.1; NP_001030126.1; NP_001030127.1; NP_001030128.1; NP_079267.1; NP_001030129.1.
Isotype	IgG
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	sorbin and SH3 domain containing 1
Database Link	NP_001030126 Entrez Gene 20411 MouseEntrez Gene 686098 RatEntrez Gene 10580 Human UniProt ID Q9BX66
Background	Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity)
Synonyms	CAP; FLAF2; R85FL; SH3D5; SH3P12; SORB1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Adherens junction, Insulin signaling pathway, PPAR signaling pathway

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