STUB1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC, PEP-ELISA, WB
Recommend Dilution	ELISA: 1:32,000. WB: 0.3-1µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-DAFISENGWVEDY, from the C Terminus of the protein sequence according to NP_005852.2.
Isotype	IgG
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	STIP1 homology and U-box containing protein 1
Database Link	NP_005852 Entrez Gene 56424 MouseEntrez Gene 287155 RatEntrez Gene 479892 DogEntrez Gene 10273 Human UniProt ID Q9UNE7
Background	Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation
Synonyms	CHIP; HSPABP2; NY-CO-7; SCAR16; SDCCAG7; UBOX1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Ubiquitin mediated proteolysis

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