TRPM7 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:64,000. WB: 0.3- 1µg/ml.
Reactivity	Mouse, Rat, Human, Dog, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-TKESESTNSVRLML, from the C Terminus of the protein sequence according to NP_060142.2.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transient receptor potential cation channel subfamily M member 7
Database Link	NP_060142 Entrez Gene 58800 MouseEntrez Gene 679906 RatEntrez Gene 478300 DogEntrez Gene 54822 Human UniProt ID Q96QT4
Background	TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants. [supplied by OMIM]
Synonyms	ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK
Reference Data
Protein Families	Druggable Genome, Ion Channels: Transient receptor potential, Protein Kinase, Transmembrane

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