FUCA2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:10~50
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This FUCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human FUCA2.
Isotype	Ig
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54061 Da
Gene Name	fucosidase, alpha-L- 2, plasma
Database Link	NP_114409 Entrez Gene 2519 Human UniProt ID Q9BTY2
Background	Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.
Synonyms	dJ20N2.5
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Other glycan degradation

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