BCL2L2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:50~100
Reactivity	Human, Mouse, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-59 amino acids from human Bcl.
Isotype	Ig
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20774 Da
Gene Name	BCL2 like 2
Database Link	NP_004041 Entrez Gene 12050 MouseEntrez Gene 599 Human UniProt ID Q92843
Background	Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Synonyms	BCL-W; BCL2-L-2; BCLW; PPP1R51
Reference Data
Protein Families	Druggable Genome, Transmembrane

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