14 3 3 gamma (YWHAG) Mouse Monoclonal Antibody [Clone ID: HS23]

Specifications

Product Data
Clone Name	HS23
Applications	ICC/IF, Immunoblotting, WB
Recommend Dilution	Immunocytochemistry/ Immunofluorescence: 1:50 - 1:250, Western Blot: 1:500 - 1:1000, Immunoblotting
Reactivity	Human, Mouse, Rat, Bovine, Chicken, Zebrafish
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody was raised against an N-terminal fragment of human 14-3-3 gamma.
Isotype	IgG1, kappa
Purification	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
Database Link	NP_036611 Entrez Gene 22628 MouseEntrez Gene 56010 RatEntrez Gene 7532 Human UniProt ID P61981
Background	14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a protein's function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints.
Synonyms	14-3-3GAMMA; PPP1R170
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

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