SIRT6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	Simple Western, WB
Recommend Dilution	Simple Western: 1:10, Western Blot: 0.5-2 ug/ml
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to an internal region of the human SIRT6 protein (within residues 250-350). [Swiss-Prot Q8N6T7]
Formulation	Tris-citrate/phosphate (pH 7-8) and 0.1% sodium azide
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	sirtuin 6
Database Link	NP_057623 Entrez Gene 51548 Human UniProt ID Q8N6T7
Background	Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing.
Synonyms	SIR2L6
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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