p60 CAF1 (CHAF1B) Mouse Monoclonal Antibody [Clone ID: SS 53]

Specifications

Product Data
Clone Name	SS 53
Applications	ICC/IF, IP, WB
Recommend Dilution	Immunocytochemistry/ Immunofluorescence, Knockdown Validated, Immunoprecipitation: 1:10-1:500, Western Blot: 1:100-1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human CAF-1p60
Isotype	IgG1
Formulation	Ascitic fluid and 0.1% sodium azide
Concentration	lot specific
Purification	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	chromatin assembly factor 1 subunit B
Database Link	NP_005432 Entrez Gene 8208 Human UniProt ID Q13112
Background	Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.
Synonyms	CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; MPHOSPH7; MPP7
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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