Carbonic Anhydrase IX (CA9) Rabbit Polyclonal Antibody

CAT#: TA301431

Rabbit Polyclonal Antibody against Carbonic Anhydrase IX



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CNY 6,188.00


货期*
5周

规格
    • 100 ul

经常一起买 (4)
Transient overexpression lysate of carbonic anhydrase IX (CA9)
    • 100 ug

CNY 3,080.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
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Recombinant protein of human carbonic anhydrase IX (CA9), 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Recombinant protein of human carbonic anhydrase IX (CA9), 100 µg
    • 100 ug

CNY 9,998.00

Specifications

Product Data
Applications ChIP, ELISA, FC, ICC/IF, IHC, Immunoblotting, IP, Simple Western, WB
Recommend Dilution Western Blot: 1 - 3 ug/ml, Proximity Ligation Assay, Gel Super Shift Assays, Simple Western: 1:50, Immunoblotting, ELISA, Immunoprecipitation: 1:10 - 1:500, Microarray, Immunohistochemistry-Paraffin: 1:200 - 1:500, Immunocytochemistry/ Immunofluorescence: 2 - 5 ug/ml, Dual RNAscope ISH-IHC: 1:1000, Chromatin Immunoprecipitation (ChIP): 1:10-1:500, Flow Cytometry: 1:1000, Immunohistochemistry: 1:200 - 1:500, Immunohistochemistry-Frozen: 1:200 - 1:500
Reactivity Human, Dog
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide derived from a C-terminal sequence of the human CA IX.
Formulation Tris-citrate/phosphate, pH 7-8, 0.1% sodium Azide
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name carbonic anhydrase 9
Background Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. Because of its functionality, it has become an important diagnostic marker for various cancers, most notably renal cell carcinoma (RCC). There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and the location of the expressed protein within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
Synonyms CAIX; MN
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Nitrogen metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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