HSD3B1 Mouse Monoclonal Antibody [Clone ID: FDO66Q]

Specifications

Product Data
Clone Name	FDO66Q
Applications	ICC/IF, IHC, WB
Recommend Dilution	Western Blot, Immunohistochemistry-Paraffin: 10-20 ug/ml, Immunohistochemistry: 10-20 ug/ml, Immunocytochemistry/ Immunofluorescence: 10-20 ug/ml, Immunohistochemistry-Frozen: 10-20 ug/ml
Reactivity	Human, Baboon, Marmoset
Host	Mouse
Clonality	Monoclonal
Immunogen	JEG Choriocarcinoma cells
Isotype	IgG1
Formulation	Tris-glycine, 150mM NaCl and 0.05% sodium azide
Concentration	lot specific
Purification	protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Database Link	NP_000853 Entrez Gene 3283 Human UniProt ID P14060
Background	3-beta hydroxysteroid dehydrogenase (HSD3B1) is a bifunctional enzyme involved in the oxidative conversion of ketosteroids that plays an important role in the synthesis of all steroid hormones. There are two HSD3B1 proteins, designated type I and type II, that are expressed by different genes and function in different areas of the body. HSD3B1 has also been shown to be a highly specific and sensitive trophoblast-associated marker (Mao et. al).
Synonyms	3BETAHSD; HSD3B; HSDB3; HSDB3A; I; SDR11E1
Reference Data
Protein Families	Transmembrane
Protein Pathways	Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways

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