LKB1 (STK11) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommend Dilution	IHC: 1:50~100, WB: 1:1000, FC: 1:10~50, IF: 1:10~50
Reactivity	Human, Mouse, Rat, Chicken, Xenopus
Host	Rabbit
Clonality	Polyclonal
Immunogen	This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	serine/threonine kinase 11
Database Link	NP_000446 Entrez Gene 20869 MouseEntrez Gene 314621 RatEntrez Gene 6794 Human UniProt ID Q15831
Background	STK11 encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Synonyms	hLKB1; LKB1; PJS
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Adipocytokine signaling pathway, mTOR signaling pathway

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