TLR7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western blot: 0.5-2.0 µg/ml. Immunocytochemistry.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a 14 amino acid sequence within mouse TLR7.
Specificity	This antibody is specific for Toll-like receptor 7 (TLR7).
Formulation	PBS containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Ion exchange chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	toll like receptor 7
Database Link	Entrez Gene 51284 Human UniProt ID Q9NYK1
Background	TLR7 is thought to play a role in the innate immune response to viral pathogens. Mouse TLR7 is localized in endosomal compartments, and recognises single stranded RNA viruses. Stimulation of TLR7 causes a type I IFN response, in a MyD88 dependent pathway.
Synonyms	Toll-like receptor 7
Reference Data

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