Nucleophosmin (NPM1) (81-294) Mouse Monoclonal Antibody [Clone ID: 5E3]

Specifications

Product Data
Clone Name	5000
Applications	ELISA, FACS, FC, ICC/IF, IF, IHC, WB
Recommend Dilution	ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on paraffin-embedded sections (1/100). Immunocytochemistry / Immonofluorescence. Flow Cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human NPM (81-294aa) purified from E. coli
Specificity	The antibody recognizes Human NPM at aa 81-294. Other species not tested.
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Database Link	NP_002511 Entrez Gene 4869 Human UniProt ID P06748
Background	Nucleophosmin (NPM; also known as B23, NO38, or numatrin) is a nucleolar phosphoprotein that binds the tumor suppressors p53 and p19Arf and is thought to be indispensable for ribogenesis, cell proliferation, and survival after DNA damage. Nucleophosmin is upregulated in many cancer cells.
Synonyms	nucleophosmin (nucleolar phosphoprotein B23,numatrin),B23, NPM, MGC104254, nucleolar phosphoprotein B23, numatrin, nucleophosmin/nucleoplasmin family, member 1
Reference Data

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