Geminin (GMNN) Mouse Monoclonal Antibody [Clone ID: 2H7]

Specifications

Product Data
Clone Name	2H7
Applications	ELISA, WB
Recommend Dilution	Western blot (1/500-1/1,000; recommended starting dilution 1/500). ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human Geminin (1-209 aa) purified from E. coli
Specificity	This antibody is specific for Geminin.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	geminin, DNA replication inhibitor
Database Link	NP_056979 Entrez Gene 51053 Human UniProt ID O75496
Background	Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
Synonyms	GMNN, Geminin, Geminin, DNA replication inhibitor, Gem, Geminin DNA replication inhibitor, OTTHuMP00000039393, RP3 369A17.3
Reference Data

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