IRF5 (176-240) Mouse Monoclonal Antibody [Clone ID: 10T1]

Specifications

Product Data
Clone Name	10T1
Applications	ELISA, FACS, FC, ICC/IF, IF, IHC, IP, WB
Recommend Dilution	ELISA. Western blot: 1/500-1/1,000. Immunoprecipitation. Immunohistochemistry on paraffin sections: 1/50. Immunocytochemistry / Immunoflourescence. Flow cytometry.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human IRF-5 (176-240aa) purified from E. coli
Specificity	The antibody recognizes Interferon Regulatory Factor 5 (IRF-5) at aa 176-240.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	interferon regulatory factor 5
Database Link	NP_116032.1 Entrez Gene 3663 Human UniProt ID Q13568
Background	Interferon regulatory factor 5 (IRF-5) is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs (IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.
Synonyms	interferon regulatory factor 5, irf5
Reference Data

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