Mrc1 Rat Monoclonal Antibody [Clone ID: MR5D3]

Specifications

Product Data
Clone Name	MR5D3
Applications	FC
Recommend Dilution	Flow Cytometry: Neat - 1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl; The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.
Specificity	This antibody recognises the mannose receptor, a 175kD type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.
Isotype	IgG2a
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: Biotin State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	mannose receptor, C type 1
Database Link	Entrez Gene 17533 Mouse UniProt ID Q61830
Background	CD206 is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
Synonyms	Macrophage mannose receptor, CLEC13D, CLEC13DL, MRC1L1
Reference Data

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