CD81 / TAPA1 Hamster Monoclonal Antibody [Clone ID: Eat2]

Specifications

Product Data
Clone Name	Eat2
Applications	FC
Recommend Dilution	Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Reactivity	Mouse
Host	Hamster
Clonality	Monoclonal
Immunogen	38C13, murine B cell line. Spleen cells from immunised Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line.
Specificity	This antibody recognises and CD81. Eat 2 induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding.
Isotype	IgG
Formulation	PBS, pH 7.4, containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified IgG fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	CD81 antigen
Database Link	Entrez Gene 12520 Mouse UniProt ID P35762
Background	CD81 is a 26kD cell surface glycoprotein that is also known as TAPA-1. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation.
Synonyms	S5.7; TAPA-1; TAPA1; Tetraspanin-28; Tspan-28; TSPAN28
Reference Data

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