CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: SN6]

Specifications

Product Data
Clone Name	SN6
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/50 diluted CD105 antibody to label 106 cells in 100 µl. Western Blot. Immunoprecipitation. Immunohistochemistry on Frozen Sections. Please note: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.
Reactivity	Equine, Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Partially purified cell membrane antigens from fresh leukemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/NS1/1-Ag4-1 myeloma cell line.
Specificity	This antibody recognises the CD105 cell surface antigen.
Isotype	IgG1
Formulation	PBS, pH7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	endoglin
Database Link	Entrez Gene 2022 Human UniProt ID P17813
Background	CD105 is a glycoprotein homodimer of 95kD subunits. CD105 is also known as endoglin, and is expressed by endothelial cells, activated monocytes and some leukaemia cells.
Synonyms	ENG, END, HHT1, ORW, ORW1
Reference Data

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