CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: 38]

Specifications

Product Data
Clone Name	38
Applications	FC, IHC, IP
Recommend Dilution	Flow cytometry: Use 5 µl of 1/50-1/100 diluted antibody to label 10e6 cells in 100 µl. Immunoprecipitation. Immunohistochemistry on Frozen Sections. Recommended Positive Control: Human Tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises the integrin alpha-L subunit, a 180kD glycoprotein expressed by all human leucocytes. The molecule is involved in cell-cell adhesion processes and binds to ICAM-1, 2 and 3.
Isotype	IgG2a
Formulation	State: Purified State: Liquid purified IgG fraction containing 0.09% Sodium Azide as preservative
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha L
Database Link	Entrez Gene 3683 Human UniProt ID P20701
Background	CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.
Synonyms	Integrin alpha-L, LFA1, LFA-1
Reference Data

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