CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: LNK16]

Specifications

Product Data
Clone Name	LNK16
Applications	FC, IP
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/10-1/20 diluted antibody to label 10e6 cells or 100 µl human whole blood. Immunoprecipitation. Does not work in Immunohistochemistry on Frozen and Paraffin Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Normal Human peripheral blood granulocytes.
Specificity	This antibody recognizes CD16. This antibody has been reported to block the binding of IgG to the CD16 molecule. (4)
Isotype	IgG1
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Fc fragment of IgG receptor IIIa
Database Link	Entrez Gene 2214 Human UniProt ID P08637
Background	CD16 is a 50-65kD cell surface molecule which exists in two forms, a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.
Synonyms	FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2
Reference Data

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