CD9 Mouse Monoclonal Antibody [Clone ID: MM2/57]

Specifications

Product Data
Clone Name	MM2/57
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of Neat-1/2 diluted antibody to label 10e6 cells or 100 µl whole blood.
Reactivity	Bovine, Canine, Equine, Feline, Human, Porcine, Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	Human platelet membrane. Spleen cells from immunised BALB/c mice were fused with cells from the SP2/0 mouse myeloma line.
Specificity	This antibody is a 24kD cell surface glycoprotein expressed by platelets, monocytes, some lymphocytes and endothelial cells. It is a member of the tetraspans gene family.
Isotype	IgG2b
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with distilled water.
Purification	Affinity chromatography on Protein A
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD9 molecule
Database Link	Entrez Gene 928 Human UniProt ID P21926
Background	CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
Synonyms	MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen
Reference Data

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