Calca Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunofluorescence: 1/800-1/1200 Incubation Time: Overnight at 2-8°C. Immunohistochemistry on Frozen and Paraffin Sections: 1/1000-1/2000 using PAP. For antigen retrieval in paraffin sections the microwave method is recommended. Positive Control: Frozen sections of Rat colon.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Calcitonin gene-related peptide, Rat (#6006, Peninsula).
Specificity	This antibody recognizes CGRP. Absorption with 10-100 µg CGRP per ml diluted antiserum abolishes the staining while Calcitonin does not. Does not cross-react with Amylin (IAPP).
Formulation	State: Serum State: Lyophilized Undiluted Serum.
Reconstitution Method	Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09% NaN3.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	calcitonin-related polypeptide alpha
Database Link	Entrez Gene 24241 Rat UniProt ID P01256
Background	The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP.
Synonyms	Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I
Reference Data

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