Plasminogen (PLG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human Angiostatin from Human plasma.
Specificity	The antibody was raised in rabbits by immunization with the Human Angiostatin from human plasma.
Formulation	Azide Free, 0.05M Phosphate buffer, 0.1M NaCl, pH 7.2 State: Aff - Purified State: Lyophilized purified IgG fraction Preservative: None
Reconstitution Method	Restore with 0.1 ml of deionized water.  Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
Concentration	1.0 mg/ml (after reconstitution)
Purification	Immunoaffinity Chromatography on a column with immobilized serum Human Angiostatin
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	plasminogen
Database Link	Entrez Gene 5340 Human UniProt ID P00747
Background	Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen. Recombinant angiostatin has 260 amino acids, residues 97-357 of human proplasminogen, and a calculated molecular mass of 29.8 kDa. The Human Angiostatin contains Kringle 1 - 4 and part of 5.
Synonyms	Plasminogen, PLG
Reference Data

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