Ptgs2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin embedded sections: 1:50-1:100 in an ABC method (30 minutes at room temperature). High temperature antigen retrieval with 10 mM citrate buffer, pH 6.0 required.  Recommended Positive Control: Lung and colon carcinoma.
Reactivity	Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein corresponding to c-terminus of rat COX2.
Specificity	This antibody reacts with a 70 kD protein. Cellular Localization: Cytoplasmic, membrane
Formulation	10 mM citrate buffer, pH 6.0 containing sodium azide as preservative. State: Purified State: Liquid purified Ig fraction.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	prostaglandin-endoperoxide synthase 2
Database Link	Entrez Gene 19225 Mouse UniProt ID Q05769
Background	COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters and cytokines that induce its expression. COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.
Synonyms	Cyclooxygenase-2, PTGS2, COX2, PHS II, PGH synthase 2, PGHS-2, PGHS2
Reference Data

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