Ezrin (EZR) Mouse Monoclonal Antibody [Clone ID: 3C12]

Specifications

Product Data
Clone Name	3C12
Applications	IHC, IP, WB
Recommend Dilution	Immunoprecipitation. Western blot: 1/100-1/750. Immunohistochemistry on Paraffin Embedded Sections: dilute 1/50-1/100 in an ABC method (30 minutes at room temperature).  Recommended Positive Control: Lung.
Reactivity	Bovine, Hamster, Human, Kangaroo, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	BALB/C mice were immunized with a recombinant fragment of Human Ezrin corresponding to amino acid 362-585.
Specificity	This antibody reacts with a protein of 70 kDa. Cellular Localization: Cell membrane.
Formulation	State: Purified State: Liquid purified Ascites Preservative: 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ezrin
Database Link	Entrez Gene 7430 Human UniProt ID P15311
Background	Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.
Synonyms	p81, Cytovillin, Villin-2, EZR, VIL2
Reference Data

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