HSP70-1A (HSPA1A) Mouse Monoclonal Antibody [Clone ID: W27]

Specifications

Product Data
Clone Name	W27
Applications	IHC
Recommend Dilution	Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1:25-1:100 in an ABC method (30-60 minutes at room temperature) Recommended Positive Control: Breast carcinoma
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	BALB/C mice were injected with purified HSP70 protein.
Specificity	This antibody is specific to constitutive (HSP73) and inducible (HSP72) form of HSP70. Cellular Localization: Cytoplasmic and nuclear
Formulation	10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative. State: Supernatant State: Liquid Ig fraction
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	heat shock protein family A (Hsp70) member 1A
Database Link	Entrez Gene 3303 Human UniProt ID P0DMV8
Background	HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides and other known proteins. HSP70 has been shown to be involved in protective role against thermal stress, cytotoxic drugs and other damaging conditions.
Synonyms	HSP70.1, HSP70-1/HSP70-2, HSPA1A, HSPA1B, HSPA1
Reference Data
Protein Pathways	Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome

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