CD66b (CEACAM8) Mouse Monoclonal Antibody [Clone ID: GM2H6]

Specifications

Product Data
Clone Name	GM2H6
Applications	ELISA, FC
Recommend Dilution	Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 µg/106 cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Genetic immunisation with cDNA encoding Human CEACAM8.
Specificity	Recognizes CEACAM8 (CD66b/NCA-95).
Isotype	IgG1
Formulation	Phosphate buffered saline, pH 7.2 without preservatives State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	carcinoembryonic antigen related cell adhesion molecule 8
Database Link	Entrez Gene 1088 Human UniProt ID P31997
Background	CEA-related cell adhesion molecule 8 (CEACAM8, CD66b) belongs to the carcinoembryonic antigen (CEA) gene family (1,3,4). It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a Mr of 95,000 which is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. CEACAM8 could serve as a marker for granulocyte activities (2). Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B do-mains.
Synonyms	CD67, CGM6, NCA-95
Reference Data

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