TAG72 Mouse Monoclonal Antibody [Clone ID: Y94]

Specifications

Product Data
Clone Name	Y94
Applications	IHC
Recommend Dilution	Immunohistochemistry on frozen and paraffin sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	Reacts with human colorectal carcinoma related protein. The selected monoclonal antibody reacts with frozen and formalin-fixed, paraffin-embedded human colorectal carcinoma tissues, but does not react with normal adult tissues tested such as liver, colon, breast, stomach, lymph node, and kidney. This antibody can detect the presence of the tumor-associated antigen in the serum of patients with colorectal carcinoma, and was shown to react with mucin-like oncofetal pancarcinoma antigen, glycoprotein TAG-72 (MW: 220-400 kDa).
Isotype	IgG1
Formulation	0.01 M PBS, pH 7.0 State: Purified State: Lyophilized
Reconstitution Method	Double distillated water is recommended to adjust the final concentration to 1.0 mg/ml
Purification	Protein G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Background	The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
Synonyms	CA72-4, CA 72-4, sialy-Tn, Tumor-Associated Glycoprotein 72
Reference Data

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