ICAM1 Mouse Monoclonal Antibody [Clone ID: 117G12.02]

Specifications

Product Data
Clone Name	117G12.02
Applications	IHC
Recommend Dilution	ImmunoHistoChemistry frozen sections, ImmunoHistoChemistry paraffin sections.  Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml.
Reactivity	Human, Sheep
Host	Mouse
Clonality	Monoclonal
Immunogen	in vitro-derived DCs (GM-CSF+TNF)
Specificity	mAb 117G2 positively stains sheep tissue sections (Schwartz-Cornil I, pers.communication ; Carlson M.et al, 1988, Nucleic Acids Res. 16 (9): 4188; Yang L. et al, 2005, Blood 106 (2): 584).
Formulation	100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8 State: Purified
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	-20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing.
Gene Name	intercellular adhesion molecule 1
Database Link	Entrez Gene 3383 Human UniProt ID P05362
Background	117G12 monoclonal antibody was obtained following mouse immunization with in vitro-derived human dendritic cells. The target antigen was found to be CD54/ICAM-1, a cell surface glycoprotein which is typically expressed on endothelial cells and immune cells. CD54/ICAM-1, member of the Ig superfamily, binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also a receptor for rhinovirus. CD54/ICAM-1 is a type of intracellular adhesion molecule, playing a role in transmigration of endothelial cells into tissues through binding to LFA-1.
Synonyms	ICAM-1
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.