Ly6g Rat Monoclonal Antibody [Clone ID: RB6-8C5]

Specifications

Product Data
Clone Name	RB6-8C5
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 10e6 cells in 100 µl.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Normal murine bone marrow cells.
Specificity	This antibody recognises the mouse Gr-1 antigen. Clone RB6-8C5 reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated. This Clone RB6-8C5 has been reported to deplete mouse mature neutrophils in vivo (3). We recommend the use of CL046LE for functional studies.
Isotype	IgG2b
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide, 1% BSA and 5% Sucrose Label: PE State: Lyophilized purified Ig fraction Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with 1 ml distilled water.
Purification	Affinity Chromatography on Protein G
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	lymphocyte antigen 6 complex, locus G
Database Link	Entrez Gene 546644 Mouse UniProt ID P35461
Background	The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported.
Synonyms	Gr-1 Granulocyte marker
Reference Data

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