MALT1 Mouse Monoclonal Antibody [Clone ID: OTI3A2]

Specifications

Product Data
Clone Name	OTI3A2
Applications	IHC
Recommend Dilution	IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MALT1 (NP_006776) produced in HEK293T cell.
Isotype	IgG2a
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	92.1 kDa
Gene Name	MALT1 paracaspase
Database Link	NP_006776 Entrez Gene 240354 MouseEntrez Gene 307366 RatEntrez Gene 10892 Human UniProt ID Q9UDY8
Background	This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms	IMD12; MLT; MLT1
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	B cell receptor signaling pathway, T cell receptor signaling pathway

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